Pakistan won the toss and opted to bat first in the second T20I at the National Stadium of Karachi on Monday.
The hosts had handed their Caribbean guests a welcome to forget in the opening T20I on Sunday, defeating them by a massive 143 runs.
But unlike the opening game, the Men in Green did not get a major contribution from their hard-hitting opener Fakhar Zaman, who chipped in just half a dozen runs and departed in the second over.
Babar Azam and Hussain Talat, however, repaired that early damage, taking their team to 42-1 at the end of 5 overs.
The duo were all warmed up and in form from the recent Pakistan Super League 2018 and they had little difficulty dealing with whatever the inexperienced Calypsos threw at them.
Halfway through their innings, Pakistan were 90-1, with a second straight 200-run output not beyond their reach.
Azam, who had a billion 50s to his name in PSL 2018, added another to his burgeoning T20I record in the 11th over.
What he could do his partner could just as well; Talat brought up his maiden 50 in the 12th over.
Pakistan: Fakhar Zaman, Babar Azam, Hussain Talat, Sarfraz Ahmed (capt, wk), Shoaib Malik, Asif Ali, Faheem Ashraf, Mohammad Nawaz, Shadab Khan, Mohammad Amir, Hasan Ali
West Indies: Chadwick Walton, Andre Fletcher, Marlon Samuels, Jason Mohammed (capt), Denesh Ramdin (wk), Rovman Powell, Keemo Paul, Rayad Emrit, Kesrick Williams, Samuel Badree, Odean Smith